R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability

R-spondin 2 mediates neutrophil egress into the alveolar space through increased lung permeability

Abstract Objective R-spondin 2 (RSPO2) is required for lung morphogenesis, activates Wnt signaling, and is upregulated in idiopathic lung fibrosis. Our objective was to investigate whether RSPO2 is similarly important in homeostasis of the adult lung. While investigating the characteristics of bronc...

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Bibliographic Details
Main Authors: S. R. Jackson, M. F. D. M. Costa, C. F. Pastore, G. Zhao, A. I. Weiner, S. Adams, G. Palashikar, K. Quansah, K. Hankenson, D. R. Herbert, A. E. Vaughan
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Research Notes
Subjects:
R-spondin 2
Neutrophil migration
Lung permeability
Lung endothelial barrier
BALF
Wnt signaling
Online Access:https://doi.org/10.1186/s13104-020-4930-8

Internet

https://doi.org/10.1186/s13104-020-4930-8

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