Oestrogen deprivation induces chemokine production and immune cell recruitment in in vitro and in vivo models of oestrogen receptor-positive breast cancer

Abstract Background Oestrogen receptor-positive (ER+) breast cancer is commonly treated using endocrine therapies such as aromatase inhibitors which block synthesis of oestradiol, but the influence of this therapy on the immune composition of breast tumours has not been fully explored. Previous find...

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Bibliographic Details
Main Authors: Jody Hazlett, Virginia Niemi, Aziz Aiderus, Katelyn Powell, Lyn Wise, Roslyn Kemp, Anita K. Dunbier
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-021-01472-1