The gamma-aminobutyric acid type B (GABA<sub>B</sub>) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens

The gamma-aminobutyric acid type B (GABA<sub>B</sub>) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens

<p>Abstract</p> <p>Background</p> <p>Repeated morphine exposure can induce behavioral sensitization. There are evidences have shown that central gamma-aminobutyric acid (GABA) system is involved in morphine dependence. However, the effect of a GABA<sub>B</sub&g...

Full description

Bibliographic Details
Main Authors: Fu Zhenyu, Yang Hongfa, Xiao Yuqiang, Zhao Gang, Huang Haiyan
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Behavioral and Brain Functions
Subjects:
GABA receptor
Morphine
Sensitization
Dopamine
Nucleus accumbens
Baclofen
Online Access:http://www.behavioralandbrainfunctions.com/content/8/1/20

Internet

http://www.behavioralandbrainfunctions.com/content/8/1/20

Similar Items