Binding of κ-Conotoxin-PVIIA to Open and Closed Shaker K-Channels Are Differentially Affected by the Ionic Strength

κ-Conotoxin-PVIIA (κ-PVIIA) is a potassium-channel blocking peptide from the venom of the fish-hunting snail, <i>Conus purpurascens</i>, which is essential for quick prey’s excitotoxic immobilization. Binding of one κ-PVIIA to <i>Shaker</i> K-channels occludes the K<sup>...

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Bibliographic Details
Main Authors: David Naranjo, Ignacio Díaz-Franulic
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/18/11/533