A clustering-independent method for finding differentially expressed genes in single-cell transcriptome data

How cell clusters are defined in single-cell sequencing data has important consequences for downstream analyses and the interpretation of results, but is often not straightforward. Here, the authors present a new approach that enables the prediction of differentially expressed genes without relying...

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Bibliographic Details
Main Authors: Alexis Vandenbon, Diego Diez
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17900-3