Impaired ventilatory and thermoregulatory responses to hypoxic stress in newborn Phox2b heterozygous knockout mice

Impaired ventilatory and thermoregulatory responses to hypoxic stress in newborn Phox2b heterozygous knockout mice

The Phox2b gene is necessary for the development of the autonomic nervous system, and especially, of respiratory neuronal circuits. In the present study, we examined the role of Phox2b in ventilatory and thermoregulatory responses to hypoxic stress, which are closely related in the postnatal period....

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Bibliographic Details
Main Authors: Nelina eRamanantsoa, Boris eMatrot, Guy eVardon, Anne-Marie eLajard, Nicolas eVoituron, Stéphane eDauger, André eDenjean, Gérard eHilaire, Jorge eGallego
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Physiology
Subjects:
Hypercapnia
hypoxia
chemosensitivity
Control of Breathing
cold
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00061/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00061/full

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