Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury

Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury

After spinal cord injury (SCI), blood-spinal cord barrier (BSCB) disruption results in secondary injury including apoptotic cell death of neurons and oligodendrocytes, thereby leads to permanent neurological deficits. Recently, we reported that the histone H3K27me3 demethylase Jmjd3 plays a role in...

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Bibliographic Details
Main Authors: Chan Sol Park, Jee Youn Lee, Hae Young Choi, Kwanghyun Lee, Yeonju Heo, Bong Gun Ju, Hae-Young Park Choo, Tae Young Yune
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Neurobiology of Disease
Subjects:
Gallic acid
Jmjd3
Blood-spinal cord barrier
Spinal cord injury
Matrix metalloprotease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120303521

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http://www.sciencedirect.com/science/article/pii/S0969996120303521

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