Methylation of the SLC6a2 gene promoter in major depression and panic disorder.

Reduced function of the noradrenaline transporter (NET) has been demonstrated in patients with major depressive disorder (MDD) and panic disorder. Attempts to explain NET dysfunction in MDD and panic disorder by genetic variation in the NET gene SLC6a2 have been inconclusive. Transcriptional silenci...

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Bibliographic Details
Main Authors: Richard Bayles, Emma K Baker, Jeremy B M Jowett, David Barton, Murray Esler, Assam El-Osta, Gavin Lambert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3847099?pdf=render