Isolation, characterization, and biological evaluation of a potent anti-malarial drimane sesquiterpene from Warburgia salutaris stem bark

Isolation, characterization, and biological evaluation of a potent anti-malarial drimane sesquiterpene from Warburgia salutaris stem bark

Abstract Background Malaria continues to be a global burden as the efficacy of most commercial anti-malarial drugs has been compromised by the evolution of parasite resistance. With the urgent need created for the development of alternative and more efficient anti-malarial drugs, this study focused...

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Bibliographic Details
Main Authors: Zoxolo N. Nyaba, Pretty Murambiwa, Andy R. Opoku, Samson Mukaratirwa, Francis O. Shode, Mthokozisi B. C. Simelane
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Anti-malarial agents
Warburgia salutaris
Iso-mukaadial acetate
Plasmodium berghei
Sprague–Dawley rats
Online Access:http://link.springer.com/article/10.1186/s12936-018-2439-6

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http://link.springer.com/article/10.1186/s12936-018-2439-6

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