Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques

Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques

Abstract This study concerns glulisine, a rapid-acting insulin analogue that plays a fundamental role in diabetes management. We have applied a combination of methods namely X-ray crystallography, and biophysical characterisation to provide a detailed insight into the structure and function of gluli...

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Bibliographic Details
Main Authors: Richard B. Gillis, Hodaya V. Solomon, Lata Govada, Neil J. Oldham, Vlad Dinu, Shahwar Imran Jiwani, Philemon Gyasi-Antwi, Frank Coffey, Andy Meal, Paul S. Morgan, Stephen E. Harding, John R. Helliwell, Naomi E. Chayen, Gary G. Adams
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81251-2

Internet

https://doi.org/10.1038/s41598-021-81251-2

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