The destructive effect of botulinum neurotoxins on the SNARE protein: SNAP-25 and synaptic membrane fusion
Synaptic exocytosis requires the assembly of syntaxin 1A and SNAP-25 on the plasma membrane and synaptobrevin 2 (VAMP2) on the vesicular membrane to bridge the two opposite membranes. It is believed that the three SNARE proteins assemble in steps along the dynamic assembly pathway. The C-terminus of...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2015-06-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/1065.pdf |