MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation

Peroxidation of cardiolipin (CL) in the inner mitochondrial membrane plays a key role in the development of various pathologies and, probably, aging. The four fatty acid tails of CL are usually polyunsaturated, which makes CL particularly sensitive to peroxidation. Peroxidation of CL is involved in...

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Bibliographic Details
Main Authors: Konstantin G. Lyamzaev, Natalia V. Sumbatyan, Alexey M. Nesterenko, Ekaterina G. Kholina, Natalia Voskoboynikova, Heinz-Jürgen Steinhoff, Armen Y. Mulkidjanian, Boris V. Chernyak
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/9710208