In Vivo Measurements of Tumor Metabolism and Growth after Administration of Enzastaurin Using Small Animal FDG Positron Emission Tomography

Background. The use of 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) may help to establish the antitumor activity of enzastaurin, a novel protein kinase C-beta II (PKC-𝛽II) inhibitor, in mouse xenografts. Methods. The hematologic cell line RAJI and the solid tumor cell line U87MG were each implanted in...

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Bibliographic Details
Main Authors: Karen E. Pollok, Michael Lahn, Nathan Enas, Ann McNulty, Jeremy Graff, Shanbao Cai, Jennifer R. Hartwell, Aaron Ernstberger, Donald Thornton, Les Brail, Gary Hutchins
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2009/596560