Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.

Individuals with partial HSA21 trisomies and mice with partial MMU16 trisomies containing an extra copy of the DYRK1A gene present various alterations in brain morphogenesis. They present also learning impairments modeling those encountered in Down syndrome. Previous MRI and histological analyses of...

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Bibliographic Details
Main Authors: Fayçal Guedj, Catherine Sébrié, Isabelle Rivals, Aurelie Ledru, Evelyne Paly, Jean C Bizot, Desmond Smith, Edward Rubin, Brigitte Gillet, Mariona Arbones, Jean M Delabar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19242551/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19242551/?tool=EBI

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