Anti-Mycobacterium tuberculosis activity and cytotoxicity of Calophyllum brasiliense Cambess (Clusiaceae)

Anti-Mycobacterium tuberculosis activity and cytotoxicity of Calophyllum brasiliense Cambess (Clusiaceae)

We evaluated the in vitro anti-Mycobacterium tuberculosis activity and the cytotoxicity of dichloromethane extract and pure compounds from the leaves of Calophyllum brasiliense. Purification of the dichloromethane extract yielded the pure compounds (-) mammea A/BB (1), (-) mammea B/BB (2) and amento...

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Bibliographic Details
Main Authors: Claudia Terencio Agostinho Pires, Mislaine Adriana Brenzan, Regiane Bertin de Lima Scodro, Diógenes Aparício Garcia Cortez, Luciana Dias Ghiraldi Lopes, Vera Lucia Dias Siqueira, Rosilene Fressatti Cardoso
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2014-06-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Mycobacterium tuberculosis
Calophyllum brasiliense
coumarin
cytotoxicity - 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300324&lng=en&tlng=en

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