Comparative Analysis of Systemic and Tumor Microenvironment Proteomes From Children With B-Cell Acute Lymphocytic Leukemia at Diagnosis and After Induction Treatment

Among the childhood diseases, B-cell acute lymphocytic leukemia (B-ALL) is the most frequent type of cancer. Despite recent advances concerning disease treatment, cytotoxic chemotherapy remains the first line of treatment in several countries, and the modifications induced by such drugs in the organ...

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Main Authors: Geise Ellen Broto, Stephany Corrêa, Fausto Celso Trigo, Everton Cruz dos Santos, Fernanda Tomiotto-Pelissier, Wander Rogério Pavanelli, Guilherme Ferreira Silveira, Eliana Abdelhay, Carolina Panis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.550213/full