Evaluation of new antihypertensive drugs designed in silico using Thermolysin as a target

The search for new therapies for the treatment of Arterial hypertension is a major concern in the scientific community. Here, we employ a computational biochemistry protocol to evaluate the performance of six compounds (Lig783, Lig1022, Lig1392, Lig2177, Lig3444 and Lig6199) to act as antihypertensi...

Full description

Bibliographic Details
Main Authors: Desmond MacLeod-Carey, Eduardo Solis-Céspedes, Emilio Lamazares, Karel Mena-Ulecia
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420300657