Immunopathogenesis of hidradenitis suppurativa and response to anti–TNF-α therapy

Immunopathogenesis of hidradenitis suppurativa and response to anti–TNF-α therapy

Hidradenitis suppurativa (HS) is a highly prevalent, morbid inflammatory skin disease with limited treatment options. The major cell types and inflammatory pathways in skin of patients with HS are poorly understood, and which patients will respond to TNF-α blockade is currently unknown. We discovere...

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Bibliographic Details
Main Authors: Margaret M. Lowe, Haley B. Naik, Sean Clancy, Mariela Pauli, Kathleen M. Smith, Yingtao Bi, Robert Dunstan, Johann E. Gudjonsson, Maia Paul, Hobart Harris, Esther Kim, Uk Sok Shin, Richard Ahn, Wilson Liao, Scott L. Hansen, Michael D. Rosenblum
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-10-01
Series:JCI Insight
Subjects:
Dermatology
Immunology
Online Access:https://doi.org/10.1172/jci.insight.139932

Internet

https://doi.org/10.1172/jci.insight.139932

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