New combination chemotherapy of cisplatin with an electron-donating compound for treatment of multiple cancers

Abstract Cisplatin is the first and most widely used platinum-based chemotherapy drug and is the cornerstone agent in treating a broad spectrum of cancers. However, its clinical application is often limited by severe toxic side effects and drug resistance. Based on the discovered dissociative electr...

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Bibliographic Details
Main Authors: Qinrong Zhang, Qing-Bin Lu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80876-z