A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast

Cellular aging is a multifactorial process that is characterized by a decline in homeostatic capacity, best described at the molecular level. Physicochemical properties such as pH and macromolecular crowding are essential to all molecular processes in cells and require maintenance. Whether a drift i...

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Bibliographic Details
Main Authors: Sara N Mouton, David J Thaller, Matthew M Crane, Irina L Rempel, Owen T Terpstra, Anton Steen, Matt Kaeberlein, C Patrick Lusk, Arnold J Boersma, Liesbeth M Veenhoff
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
pH
Online Access:https://elifesciences.org/articles/54707