Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution

<p>Abstract</p> <p>Background</p> <p>Vaccination of macaques with live attenuated simian immunodeficiency virus (SIV) provides significant protection against the wild-type virus. The use of a live attenuated human immunodeficiency virus (HIV) as AIDS vaccine in humans i...

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Bibliographic Details
Main Authors: Piatak Mike, Yuan Fang, Almond Neil, Page Mark, Ooms Marcel, Harwig Alex, Centlivre Mireille, Klaver Bep, Das Atze T, Lifson Jeffrey D, Berkhout Ben
Format: Article
Language:English
Published: BMC 2008-06-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/44