Granulomatous response to Coxiella burnetii, the agent of Q fever: the lessons from gene expression analysis

Granulomatous response to Coxiella burnetii, the agent of Q fever: the lessons from gene expression analysis

The formation of granulomas is associated with the resolution of Q fever, a zoonosis due to Coxiella burnetii; however the molecular mechanisms of granuloma formation remain poorly understood. We generated human granulomas with peripheral blood mononuclear cells and beads coated with C. burnetii, us...

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Bibliographic Details
Main Authors: delphine efaugaret, amira eben amara, julie ealingrin, aurelie edaumas, amelie edelaby, catherine elepolard, didier eraoult, julien etextoris, Jean-Louis eMege
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Coxiella burnetii
Gene Expression
Granuloma
Interferon Type I
Q Fever
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00172/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00172/full

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