Using network component analysis to dissect regulatory networks mediated by transcription factors in yeast.

Understanding the relationship between genetic variation and gene expression is a central question in genetics. With the availability of data from high-throughput technologies such as ChIP-Chip, expression, and genotyping arrays, we can begin to not only identify associations but to understand how g...

Full description

Bibliographic Details
Main Authors: Chun Ye, Simon J Galbraith, James C Liao, Eleazar Eskin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2649002?pdf=render