Using network component analysis to dissect regulatory networks mediated by transcription factors in yeast.
Understanding the relationship between genetic variation and gene expression is a central question in genetics. With the availability of data from high-throughput technologies such as ChIP-Chip, expression, and genotyping arrays, we can begin to not only identify associations but to understand how g...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2649002?pdf=render |