Low serum klotho concentration is associated with worse cognition, psychological components of frailty, dependence, and falls in nursing home residents
Abstract Serum alpha-klotho (s-klotho) protein has been linked with lifespan, and low concentrations of s-klotho have been associated with worse physical and cognitive outcomes. Although its significance in aging remains unclear, s-klotho has been proposed as a molecular biomarker of frailty and dep...
Main Authors: | Begoña Sanz, Haritz Arrieta, Chloe Rezola-Pardo, Ainhoa Fernández-Atutxa, Jon Garin-Balerdi, Nagore Arizaga, Ana Rodriguez-Larrad, Jon Irazusta |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-88455-6 |
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