Low serum klotho concentration is associated with worse cognition, psychological components of frailty, dependence, and falls in nursing home residents

Abstract Serum alpha-klotho (s-klotho) protein has been linked with lifespan, and low concentrations of s-klotho have been associated with worse physical and cognitive outcomes. Although its significance in aging remains unclear, s-klotho has been proposed as a molecular biomarker of frailty and dep...

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Bibliographic Details
Main Authors: Begoña Sanz, Haritz Arrieta, Chloe Rezola-Pardo, Ainhoa Fernández-Atutxa, Jon Garin-Balerdi, Nagore Arizaga, Ana Rodriguez-Larrad, Jon Irazusta
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88455-6