Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment

Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment

Abstract Background Novel therapeutic approaches are required to treat ovarian cancer and dependency on glycolysis may provide new targets for treatment. This study sought to investigate the variation of expression of molecular components (GLUT1, HKII, PKM2, LDHA) of the glycolytic pathway in ovaria...

Full description

Bibliographic Details
Main Authors: Chrysi Xintaropoulou, Carol Ward, Alan Wise, Suzanna Queckborner, Arran Turnbull, Caroline O. Michie, Alistair R. W. Williams, Tzyvia Rye, Charlie Gourley, Simon P. Langdon
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Cancer
Subjects:
Ovarian cancer
Glycolytic pathway
Inhibitors
Combination strategies
Cisplatin
Metformin
Online Access:http://link.springer.com/article/10.1186/s12885-018-4521-4

Internet

http://link.springer.com/article/10.1186/s12885-018-4521-4

Similar Items