Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.

Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.

A major therapeutic challenge is how to replace bone once it is lost. Bone loss is a characteristic of chronic inflammatory and degenerative diseases such as rheumatoid arthritis and osteoporosis. Cells and cytokines of the immune system are known to regulate bone turnover by controlling the differe...

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Bibliographic Details
Main Authors: Vicky Nicolaidou, Mei Mei Wong, Andia N Redpath, Adel Ersek, Dilair F Baban, Lynn M Williams, Andrew P Cope, Nicole J Horwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3389003?pdf=render

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http://europepmc.org/articles/PMC3389003?pdf=render

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