Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation.

Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation.

Recycling endosomes regulate plasma membrane recycling. Recently, recycling endosome-associated proteins have been implicated in the positioning and orientation of the mitotic spindle and cytokinesis. Loss of MYO5B, encoding the recycling endosome-associated myosin Vb, is associated with tumor devel...

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Bibliographic Details
Main Authors: Changsen Leng, Arend W Overeem, Fernando Cartón-Garcia, Qinghong Li, Karin Klappe, Jeroen Kuipers, Yingying Cui, Inge S Zuhorn, Diego Arango, Sven C D van IJzendoorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000531

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https://doi.org/10.1371/journal.pbio.3000531

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