Epithelial to mesenchymal transition of a primary prostate cell line with switches of cell adhesion modules but without malignant transformation.

BACKGROUND: Epithelial to mesenchymal transition (EMT) has been connected with cancer progression in vivo and the generation of more aggressive cancer cell lines in vitro. EMT has been induced in prostate cancer cell lines, but has previously not been shown in primary prostate cells. The role of EMT...

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Bibliographic Details
Main Authors: Xi-Song Ke, Yi Qu, Naomi Goldfinger, Kari Rostad, Randi Hovland, Lars A Akslen, Varda Rotter, Anne Margrete Øyan, Karl-Henning Kalland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2557125?pdf=render