Noradrenaline Sensitivity Is Severely Impaired in Immortalized Adipose-Derived Mesenchymal Stem Cell Line

Noradrenaline Sensitivity Is Severely Impaired in Immortalized Adipose-Derived Mesenchymal Stem Cell Line

Primary adipose tissue-derived multipotent stem/stromal cells (adMSCs) demonstrate unusual signaling regulatory mechanisms, i.e., increased of sensitivity to catecholamines in response to noradrenaline. This phenomenon is called “heterologous sensitization”, and was previously found only in embryoni...

Full description

Bibliographic Details
Main Authors: Pyotr A. Tyurin-Kuzmin, Vadim I. Chechekhin, Anastasiya M. Ivanova, Daniyar T. Dyikanov, Veronika Y. Sysoeva, Natalia I. Kalinina, Vsevolod A. Tkachuk
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
mesenchymal stem/stromal cells
noradrenaline
norepinephrine
intracellular signaling
membrane receptors
adrenergic receptors
calcium imaging
ASC52telo
hTERT
Online Access:https://www.mdpi.com/1422-0067/19/12/3712

Internet

https://www.mdpi.com/1422-0067/19/12/3712

Similar Items