Levels of uPA and PAI-1 in breast cancer and its correlation to Ki67-index and results of a 21-multigene-array

Abstract Background Conventional parameters including Ki67, hormone receptor and Her2/neu status are used for risk stratification for breast cancer. The serine protease urokinase plasminogen activator (uPA) and the plasminogen activator inhibitor type-1 (PAI-1) play an important role in tumour invas...

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Bibliographic Details
Main Authors: Hans-Ullrich Völker, Michael Weigel, Annette Strehl, Lea Frey
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Diagnostic Pathology
Subjects:
uPA
Online Access:http://link.springer.com/article/10.1186/s13000-018-0737-5