Levels of uPA and PAI-1 in breast cancer and its correlation to Ki67-index and results of a 21-multigene-array
Abstract Background Conventional parameters including Ki67, hormone receptor and Her2/neu status are used for risk stratification for breast cancer. The serine protease urokinase plasminogen activator (uPA) and the plasminogen activator inhibitor type-1 (PAI-1) play an important role in tumour invas...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-08-01
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Series: | Diagnostic Pathology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13000-018-0737-5 |