Immune-Mediated Damage Completes the Parabola: Cryptococcus neoformans Pathogenesis Can Reflect the Outcome of a Weak or Strong Immune Response

Cryptococcosis occurs most frequently in immunocompromised individuals. This has led to the prevailing view that this disease is the result of weak immune responses that cannot control the fungus. However, increasingly, clinical and experimental studies have revealed that the host immune response ca...

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Bibliographic Details
Main Authors: Liise-anne Pirofski, Arturo Casadevall
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e02063-17