In silico single-molecule manipulation of DNA with rigid body dynamics.

We develop a new powerful method to reproduce in silico single-molecule manipulation experiments. We demonstrate that flexible polymers such as DNA can be simulated using rigid body dynamics thanks to an original implementation of Langevin dynamics in an open source library called Open Dynamics Engi...

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Bibliographic Details
Main Authors: Pascal Carrivain, Maria Barbi, Jean-Marc Victor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3930497?pdf=render