Regulation of Formation, Stemness and Therapeutic Resistance of Cancer Stem Cells

Over the past 20 years cancer stem cells (CSCs) have been proposed as key players in the tumorigenesis and progression, which are closely related to the initiation, metastasis and therapeutic resistance of cancer. Evidences have been provided that both genetic and epigenetic factors contribute to th...

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Bibliographic Details
Main Authors: Nan Jing, Wei-Qiang Gao, Yu-Xiang Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.641498/full