Signaling Pathways Regulated by UBR Box-Containing E3 Ligases

UBR box E3 ligases, also called N-recognins, are integral components of the N-degron pathway. Representative N-recognins include UBR1, UBR2, UBR4, and UBR5, and they bind destabilizing N-terminal residues, termed N-degrons. Understanding the molecular bases of their substrate recognition and the bio...

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Bibliographic Details
Main Authors: Jung Gi Kim, Ho-Chul Shin, Taewook Seo, Laxman Nawale, Goeun Han, Bo Yeon Kim, Seung Jun Kim, Hyunjoo Cha-Molstad
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/15/8323