Comprehensive Genomic Investigation of Coevolution of mcr genes in Escherichia coli Strains via Nanopore Sequencing

Abstract Horizontal gene transfer facilitates the spread of antibiotic resistance genes, which constitutes a global challenge. However, the evolutionary trajectory of the mobile colistin resistome in bacteria is largely unknown. To investigate the coevolution and fitness cost of the colistin resista...

Full description

Bibliographic Details
Main Authors: Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Xiaorong Yang, Zhiqiang Wang, Juan Wang, Li Bai
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Global Challenges
Subjects:
Online Access:https://doi.org/10.1002/gch2.202000014