Second site escape of a T20-dependent HIV-1 variant by a single amino acid change in the CD4 binding region of the envelope glycoprotein
<p>Abstract</p> <p>Background</p> <p>We previously described the selection of a T20-dependent human immunodeficiency virus type-1 (HIV-1) variant in a patient on T20 therapy. The fusion inhibitor T20 targets the viral envelope (Env) protein by blocking a conformational...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-11-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/3/1/84 |