STAT3 Modulates Cigarette Smoke-Induced Inflammation and Protease Expression

STAT3 Modulates Cigarette Smoke-Induced Inflammation and Protease Expression

Signal transducer and activator of transcription-3 (STAT3) regulates inflammation, apoptosis and protease expression, which are critical processes associated with airway injury and lung tissue destruction. However, the precise role of STAT3 in the development of airway diseases such as chronic obstr...

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Bibliographic Details
Main Authors: Patrick eGeraghty, Anne Elizabeth Wyman, Itsaso eGarcia-Arcos, Abdoulaye Jules Dabo, Sonya eGadhvi, Robert eForonjy
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Physiology
Subjects:
Apoptosis
Cytokines
Inflammation
Lung
COPD
signaling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00267/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00267/full

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