CAR-NK cell therapeutics for hematologic malignancies: hope is on the horizon

Abstract. Chimeric antigen receptor (CAR)-T-cell therapy has achieved significant success in the treatment of hematologic malignancies. However, treatment-related toxicity and side effects remain the major drawbacks. As an important effector cell in innate immunity, natural killer (NK) cells exert s...

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Bibliographic Details
Main Authors: Kai-lin Xu, Hai Cheng
Format: Article
Language:English
Published: Wolters Kluwer Health 2019-10-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000028