Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models

An established pharmaceutical strategy to increase oral drug absorption of low solubility–high permeability drugs is to create nanoparticles of them. Reducing the size of the solid-state particles increases their dissolution and transport rate across the mucus barrier and the aqueous boundary layer...

Full description

Bibliographic Details
Main Authors: David Dahlgren, Erik Sjögren, Hans Lennernäs
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2020-09-01
Series:ADMET and DMPK
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/881