TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes

Abstract Potassium channels from prokaryotes and eukaryotes are usually recognized by a typical amino acid sequence TXTGY(F)G representing the ionic selectivity filter. Using a screening approach with ion channel family profiles but without the above motif, we identified a gene in Trypanosoma brucei...

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Bibliographic Details
Main Authors: Michael E. Steinmann, Remo S. Schmidt, Peter Bütikofer, Pascal Mäser, Erwin Sigel
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00752-1