Free fatty acids reduce metabolic stress and favor a stable production of heterologous proteins in Pichia pastoris

ABSTRACT The growth of yeasts in culture media can be affected by many factors. For example, methanol can be metabolized by other pathways to produce ethanol, which acts as an inhibitor of the heterologous protein production pathway; oxygen concentration can generate aerobic or anaerobic environment...

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Bibliographic Details
Main Authors: Andrea B. Zepeda, Carolina A. Figueroa, Adalberto Pessoa, Jorge G. Farías
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia
Series:Brazilian Journal of Microbiology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000400856&lng=en&tlng=en