Synthesis, antimicrobial and cytotoxic activities of 5-benzylidene-2-[(pyridine-4-ylmethylene)hydrazono]-thiazolidin-4-one and 2-[(pyridine-4-ylmethylene) hydrazono]-thiazolidin-4-one derivatives

Synthesis, antimicrobial and cytotoxic activities of 5-benzylidene-2-[(pyridine-4-ylmethylene)hydrazono]-thiazolidin-4-one and 2-[(pyridine-4-ylmethylene) hydrazono]-thiazolidin-4-one derivatives

A new series of 5-benzylidene-2-[(pyridine-4-ylmethylene)hydrazono]-thiazolidin-4-ones 4a-l have been synthesized. These compounds were designed by a molecular hybridization approach. 2-[(Pyridine-4-ylmethylene)hydrazono]-thiazolidin-4-ones 3a-d were also obtained and used as intermediates to give t...

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Bibliographic Details
Main Authors: Danniel Delmondes Feitoza, Antônio José Alves, José Gildo de Lima, Janete Magali Araújo, Jaciana Santos Aguiar, Maria do Desterro Rodrigues, Teresinha Gonçalves Silva, Silene Carneiro do Nascimento, Alexandre José da Silva Góes
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2012-01-01
Series:Química Nova
Subjects:
4-thiazolidinone
molecular hybridization
antimicrobial and cytotoxic activities
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000400007&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000400007&lng=en&tlng=en

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