Swept-sine noise-induced damage as a hearing loss model for preclinical assays

Mouse models are key tools for studying cochlear alterations in noise-induced hearing loss and for evaluating new therapies. Stimuli used to induce deafness in mice are usually white and octave band noises that include very low frequencies, considering the large mouse auditory range. We designed dif...

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Bibliographic Details
Main Authors: Lorena eSanz, Silvia eMurillo-Cuesta, Pedro eCobo, Rafael eCediel, Julio eContreras, Teresa eRivera, Isabel eVarela-Nieto, Carlos eAvendaño
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00007/full