A chromosome-level Camptotheca acuminata genome assembly provides insights into the evolutionary origin of camptothecin biosynthesis

Camptothecin is a monoterpene indole alkaloid with anti-tumor activity. Here, the authors assemble the genome of the camptothecin producing plant Camptotheca acuminata and provide insights into the evolutionary origin of camptothecin biosynthesis by comparing to the vinblastine and vincristine biosy...

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Bibliographic Details
Main Authors: Minghui Kang, Rao Fu, Pingyu Zhang, Shangling Lou, Xuchen Yang, Yang Chen, Tao Ma, Yang Zhang, Zhenxiang Xi, Jianquan Liu
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23872-9