Minimal residual disease negativity by next-generation flow cytometry is associated with improved organ response in AL amyloidosis

Minimal residual disease negativity by next-generation flow cytometry is associated with improved organ response in AL amyloidosis

Abstract Light chain (AL) amyloidosis is caused by a small B-cell clone producing light chains that form amyloid deposits and cause organ dysfunction. Chemotherapy aims at suppressing the production of the toxic light chain (LC) and restore organ function. However, even complete hematologic response...

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Bibliographic Details
Main Authors: Giovanni Palladini, Bruno Paiva, Ashutosh Wechalekar, Margherita Massa, Paolo Milani, Marta Lasa, Sriram Ravichandran, Isabel Krsnik, Marco Basset, Leire Burgos, Mario Nuvolone, Ramón Lecumberri, Andrea Foli, Noemi Puig, Melania Antonietta Sesta, Margherita Bozzola, Pasquale Cascino, Alice Nevone, Jessica Ripepi, Pierpaolo Berti, Simona Casarini, Ombretta Annibali, Alberto Orfao, Jesus San-Miguel, Giampaolo Merlini
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-021-00428-0

Internet

https://doi.org/10.1038/s41408-021-00428-0

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