Tempol treatment reduces anxiety-like behaviors induced by multiple anxiogenic drugs in rats.

We have published that pharmacological induction of oxidative stress (OS) causes anxiety-like behavior in rats. Using animal models, we also have established that psychological stress induces OS and leads to anxiety-like behaviors. All evidence points towards the causal role of OS in anxiety-like be...

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Bibliographic Details
Main Authors: Gaurav Patki, Ankita Salvi, Hesong Liu, Fatin Atrooz, Isam Alkadhi, Matthew Kelly, Samina Salim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4367986?pdf=render