Chiral Phosphoric Acid Promoted Chiral 1H NMR Analysis of Atropisomeric Quinolines

An efficient enantioselective NMR analysis of atropisomeric quinolines in the promotion of chiral phosphoric acid is described, in which a variety of racemic 4-aryl quinolines were well-recognized with up to 0.17 ppm ΔΔδ value. Additionally, the optical purities of different nonracemic substrates co...

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Bibliographic Details
Main Authors: Junlin Wan, Jun Jiang, Juan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.672704/full