Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter

Regulation of calretinin in malignant mesothelioma is mediated by septin 7 binding to the CALB2 promoter

Abstract Background The calcium-binding protein calretinin (gene name: CALB2) is currently considered as the most sensitive and specific marker for the diagnosis of malignant mesothelioma (MM). MM is a very aggressive tumor strongly linked to asbestos exposure and with no existing cure so far. The m...

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Bibliographic Details
Main Authors: Walter Blum, László Pecze, Janine Wörthmüller Rodriguez, Martine Steinauer, Beat Schwaller
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
Calretinin
Septin 7
Malignant mesothelioma
Transcriptional regulation
Butyrate
Online Access:http://link.springer.com/article/10.1186/s12885-018-4385-7

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http://link.springer.com/article/10.1186/s12885-018-4385-7

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