Determination of cefcapene acid by LCâMS and their application to a pharmacokinetic study in healthy Chinese volunteers

Simple, rapid and specific liquid chromatographyâmass spectrometry (LCâMS) methods have been developed and validated for the quantification of cefcapene acid in human plasma and urine. Plasma samples were simply pretreated with methanol for deproteinization. Urine samples were briefly diluted with m...

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Bibliographic Details
Main Authors: Hong-Fei Duan, Li Ding, Xiao-Bing Li, Lin-Lin Hu, Ai-Dong Wen, Ye Leng, Zhen Liu
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S209517791200113X